Myopericarditis

Myopericarditis following smallpox vaccination.

Myopericarditis has been a rare or unrecognized event after smallpox vaccinations with the New York City Board of Health strain of vaccinia virus (Dryvax; Wyeth Laboratories, Marietta, Pennsylvania). In this article, the authors report an attributable incidence of at least 140 clinical cases of myopericarditis per million primary smallpox vaccinations with this strain of vaccinia virus. Fifty-e...

Myopericarditis: A Diagnosis of Uncertainty

Myocarditis can present in many different forms and can be overlooked by more life-threatening conditions. At times it may mimic conditions such as acute myocardial infarction and although it may have features highly suggestive of myocarditis, other etiologies need to be excluded. Thus, due to its clinical presentation, lab findings, and electrocardiogram analysis, it often can be confused with...

Four faces of acute myopericarditis.

A successful re-trial after clozapine myopericarditis.

Clozapine-induced myopericarditis is a well-described adverse drug reaction. Clozapine is also the most efficacious agent in refractory schizophrenia. We report a case of a patient who was successfully re-trialled on clozapine two years after developing myopericarditis, after which multiple lines of alternative treatment failed. We propose a protocol for safely attempting a re-trial of clozapin...

Myopericarditis as an Initial Presentation of Meningococcemia

From the Cardiovascular and Infectious Disease Divisions, Department of Medicine, Brigham and Women’s Hospital and Harvard Medical School, Boston, Massachusetts. This work was supported in part by Grant 5432 HL-07049 from the National Heart, Lung, and Blood Institute, Bethesda, Maryland. Requests for reprints shuld be addressed to Dr. James M. Kirshenbaum, Cardiovascular Division, Brigham and W...